Attenuation of Methotrexate-induced Kidney Toxicity in Rat Model by Antioxidants
Cancer is a major burden of disease worldwide. Cancer treatment involves the use of chemotherapy which employs a wide group of drugs that have cytotoxic effects which preferentially, but not exclusively, target the rapidly dividing cancer cells (Cholawara et al., 2011). Chemotherapeutic agents include methotrexate...