Report On Compounding: History, Roles, Research And Development

Introduction

Compounding can be defined as, it’s the creation of a selected pharmaceutical product which contains the ability to show perfect therapeutic effect.

History

We know that the term pharmacy came from the word Pharmacon which means drug. After the discovery of the pharmacy, the scientists thought that how they would be able to produce perfect medicine and from this the term doses form, prescription, pharmaceutical compounding came. The actual experiment of preparing medications dates back to the origins of pharmacy, yet, compounding's presence throughout the pharmacy profession has changed over the years.

During the age 1930, 1940, mostly 60 percent of most of the medications were perfectly compounded and during the age 1950 and also1960, with the advent of manufacturing and preparing, compounding declined. The role of the pharmacists as a preparer of medications quickly changed to that of a dispenser of prepared dosage forms for perfect therapeutic effect. During the period of 1980 and in the1990, physicians, pharmacists and patients again began realizing the benefits of preparing customized medications to meet specific patient needs for a perfect therapeutic response.

Roles

1. Research and Development

The term pharmaceutical compounding is a large branch of pharmacy that always play an important role in the development of each drugs. The pharmacists and medicine related chemists develop and test combinations of API and delivery systems for new pharmaceutical chemical formulation so that the API are effective, stable, easy to use, and acceptable to patients for perfect mode of action and therapeutic response.

2. Polypharmacy

The term poly-pharmacy and compounding are related with each other and for the discussion of poly-pharmacy for perfect knowledge we have to discuss the term with personal medication. The term poly-pharmacy can be defined as it is the concurrent use of multiple medications by a patient. When the actual regulatory boundaries are not always clear when a patient can’t get perfect therapeutic effect for produce perfect therapeutic response by using a drug the physicians have submitting of prescription of customized drug products which contain unique drug dosage formulations for individual patients, and those doses or those new drug products have to prepare by a pharmacist or medicinal chemist and in here compounding play an important role.

3. Personalized Medicine

We know that our genome contain a unique variation and which can be discussed by bioscience. And also maybe we know that, 80 percent of the variation between tow or more individuals has no power to show effect on our health, an individual's health stems from genetic variation with behaviors and influences from the environment this concept is proved by medical science. The modern technology in personalized medicine technology rely on technology that confirms a patient's fundamental biology like Protein, DNA or RNA which ultimately play rule to confirming a disease. As example, we can say the personalized techniques such as genome sequencing can reveal mutations in DNA that influence diseases ranging from cystic fibrosis to cancer. The ideas which are collected from personalized medicine can be applied to new and transformative approaches to health care. The personalized health care is based on the dynamics of systems biology and uses predictive tools to evaluate health risks and to design personalized health plans to help patients mitigate risks, prevent disease and to treat it with precision when it occurs. So we can say this part is relate with the idea gaining, genetic activity and drugs dose preparation.

Country wise Activity

We know that pharmacy deals with life and works with the disease so for perfect treatment of disease the modern countries follow some important roles which play important rule into the profession of pharmacy. As example we can be able to discuss about Australia and USA. At first we can discuss about the pharmacy profession of Australia in Australia the Pharmacy Board of Australia which is also popularly known as PBA is fully related with the submitting of registration of pharmacists which is related with the license and drug manufacturing practice including compounding. All pharmacies are able to make at least normal compounded medicines, and there are also some pharmacies which arrange training and education system for make more complex products The whole world know that for medical science United State of America is most powerful and they are developed. It’s happened only for their perfect rules and regulation. In the pharmacy field they arranged a lot of selected groups which maintain and regulate the whole pharmacy sector. In compounding also there is an established group which maintain this sector. In USA compounding pharmacies contain a license and these pharmacies are maintained by their states as like as all other model pharmacies their national standards create by PCAB which is also popularly known as Pharmacy Compounding Accreditation Board.

Importance of Compounding

1. We are living into the age of modern world every sector of life is now more developed then the past. Today every parts of life science is also developing. Now peoples want the highest quality in every sector also in medication and for making perfect medicine compounding pharmacies have to ensure the highest quality of pharmaceutical ingredients and which can confirm the prescription using the latest research, quality control process, and techniques that play an important role to meet the individual patient needs.
2. There are some medications which contain a very unsuitable flavor, compounding play an important role in preparing perfect dose which contain a suitable flavor and which produce by pharmacists or chemists.

Application

The term compounding discuss the preparation of perfect therapeutic dose for getting a perfect therapeutic response. For creating therapeutic response into every part of body compounding is important so we can say compounding regulate the preparing of perfect doses.